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Glucosamine and Chondroitin Side Effects
Posted by Amy Clark at Feb 2nd, 2009 in Arthritis
Your body manufactures a natural substance called Glucosamine which is made from glucose and glutamine (an amino acid). Glucosamine might also be described as an amino sugar synthesized from glucose and L-glutamine.
Glucosamine has many alternative names, like for example: N-acetyl glucosamine, glucosamine sulfate, and glucosamine hydrochloride.
Glycosaminoglycan, meanwhile, is a molecule that is relevant in the development or restoration of your cartilage and other tissues throughout the body. As you grow older, the body’s production of Glycosaminoglycan diminishes, hence causing swelling and bloating in the joints.
Glucosamine and chondroitin function as building blocks of the connective tissues and the cartilage. Glucosamine supplements are natural substances that occur naturally in shellfish harvests.
Glucosamine is commonly used with chondroitin to manage the symptoms of osteoarthritis (a.k.a. OA). Medical research has established that the Glucosamine-Chondroitin combination is effective in osteoporosis treatment and gradually repairing bone function.
Glucosamine Chondroitin: Potential Side Effects
By and large, nearly all supplements have their own risks for negative side effects. Glucosamine and Chondroitin have demonstrated remarkable results in clinical trials, with most patients reporting no side effects.
However, in a few cases, some individuals may experience a slight increase in blood pressure, breathing difficulties, uneasiness, rashes, nausea, mild headaches, as well as upset stomachs or gastrointestinal pains.
One of the most common side effects of glucosamine-chondroitin supplements is soft stools and increased intestinal gas, but this is very rare. Clinical researches using animals reveal that glucosamine may lessen insulin levels, which can cause diabetes. Although this has not occurred in human tests, diabetic patients are still advised to be careful and regularly check their blood sugar when using glucosamine.
Additionally, patients who are taking aspirins or blood thinners must visit their physician prior to using these supplements. Similarly, pregnant women or women who want to get pregnant should also get proper medical advice, specifically because the effects of these supplements on a developing fetus is yet unknown. Children and women who are breast feeding should stay away from glucosamine completely.
At present, different clinical studies continue to evaluate and assess the long-term consequences of glucosamine chondroitin supplements. All things considered, while their long-term repercussions are yet a mystery, the majority of experts share the collective opinion that the combined benefits of glucosamine & chondroitin sulfate in treating OA overshadow any potential risks.
Glucosamine with chondroitin is probably the single most potent supplement for lubricating, maintaining, and protecting the joints. Additionally, glucosamine restrains the movement of your joints and consequently prevent the weakening of the joint cartilage. Various studies have proven the potency of glucosamine in pain management and treating osteoarthritis symptoms, although such outcomes were not immediately available. Moreover, Glucosamine is also believed to lessen inflammation of the joints and block harmful enzymes that may damage the cartilage, though further studies on this aspect are needed.
Tags: Arthritis
There's good breeders, there's bad breeders. I've met lots of cat breeders at shows. True cat breeders are doing so to better the breed and don't breed simply to churn out mass amounts of kittens to sell. Many have only one or two breeding males and one or two breeding females and only a litter or two each year. Most catteries are like that. And if you're in the market for a purebred cat or kitten - and can't find one at a shelter - then look up a local breeder and you'll be able to go there and check out the facility. Which is why you DON'T buy cats or kittens at pet stores. They don't tend to buy from reputable breeders - they buy what's cheap.
There are, however, some that breed to the trends - not to better the breed. I've heard of miniature Persians and other "breeds" that these people are breeding. It's not out of love of the animal or respect for the breed - they're doing it to appeal to idiotic people who think a "trendy" cat like this is desirable - when in reality it often means a very sick, inbred cat. It's basically the dog equivalent of the sickly "teacup" Yorkies, Chihuahuas, etc.
Hoarders don't breed animals to sell them. They tend to take in every stray even though financially they can't afford to care for them and they just keep taking in more and more. They generally don't bother spaying and neutering so more and more kittens are born. Hoarders also tend to not seek medical treatment when the animals are ill and their homes are a nightmare. They're the ones you'll see on Animal Planet on the animal shows saying they did it because they "love" animals and don't see anything wrong with the way they're living. For more about hoarding click here -
Supposedly this is a form of obsessive/compulsive disorder but sorry - I don't feel any pity for a hoarder if animals are being treated badly.
One of the issues that has always bugged me about this is the issue of context - medicine has a great track record in treating emergencies, but fares quite poorly with preventative care and chronic illness.
The issue arises when people associate the good track record of emergency care with preventative treatment - so essentially take what’s prescribed as gospel.Would you take investment advice from a great pig farmer? Dental advice from a good banker? Art advice from a physicist?
I would imagine that pharma will have to tread very carefully over the next decade, as the cumulative resuls of drug-trials like these start to create an interesting track record. However, spin-doctoring is everything….
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So if we use the SWAG developed above - up to the mid 1950 and (simply because I’m getting tired and have to be up in 5 hours) put in a stub for the calculation of the years since then (I assume rate of decline constant over that period but haven’t gone to look) and guess at a total humans born count of 106,457,367,669 (through 2002) and some other figures I wont list here for the periods of up to mid 19th and segments between then and now I get an average rate across all time of between 64% and 81%
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